Varaico: Literature-Extracted Genetic Variants

Gene:PPP2CA
Variant:p.R115*

PPP2CA

93 papers

RefSeq Summary

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. ...

Pfam Domains

Metallophosaa 50–245UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 2 catalytic subunit alpha

HGNC Alias Symbols

PP2Calpha; PP2AC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002715.4
p.R115*
c.343C>T
Surrounding Variants
1 paper
NM_002715.4
p.N117K
c.351T>G
1 paper
NM_002715.4
p.N117K
c.351T>A
1 paper
NM_002715.4
p.H118Y
c.352C>T
2 papers
NM_002715.4
p.H118N
c.352C>A
1 paper
NM_002715.4
p.H118R
c.353A>G
5 papers
NM_002715.4
p.Q122H
c.366G>T
5 papers
NM_002715.4
p.Q122H
c.366G>C
1 paper
NM_002715.4
p.R106H
c.317G>A
1 paper
NM_002715.4
p.T124A
c.370A>G
1 paper
NM_002715.4
p.V105I
c.313G>A
7 papers
NM_002715.4
p.Q125*
c.373C>T
2 papers
NM_002715.4
p.Y127N
c.379T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."