Varaico: Literature-Extracted Genetic Variants

PPP2R1B

94 papers

RefSeq Summary

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell grow...

Pfam Domains

2AA_helicalaa 96–285UCSCPhosphatase 2A Regulatory Subunit A, helical domain

PPP2R1A-like_HEATaa 288–369UCSCPPP2R1A-like HEAT repeat

HEAT_2aa 378–479UCSCHEAT repeats

HEATaa 494–524UCSCHEAT repeat

Gene Aliases

HGNC Name

protein phosphatase 2 scaffold subunit Abeta

HGNC Alias Symbols

PR65B; PP2A-Abeta

Papers

RefSeq ID

Protein change

DNA change

1–12 of 88 variants

13 papers

NM_002716.5

p.G90D

c.269G>A

6 papers

NM_002716.5

p.P65S

c.193C>T

4 papers

NM_002716.5

p.R270C

c.808C>T

4 papers

NM_002716.5

p.K343E

c.1027A>G

4 papers

NM_002716.5

p.K354R

c.1061A>G

4 papers

NM_002716.5

p.D504G

c.1511A>G

3 papers

NM_002716.5

p.L101P

c.302T>C

3 papers

NM_002716.5

p.T114_V115delFs

c.342_343delCA

3 papers

NM_002716.5

p.R311W

c.931C>T

3 papers

NM_002716.5

p.V545A

c.1634T>C

3 papers

NM_002716.5

p.R549C

c.1645C>T

3 papers

NM_002716.5

p.I559F

c.1675A>T