Varaico: Literature-Extracted Genetic Variants

PPP2R1B

94 papers

RefSeq Summary

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell grow...

Pfam Domains

2AA_helicalaa 96–285UCSCPhosphatase 2A Regulatory Subunit A, helical domain

PPP2R1A-like_HEATaa 288–369UCSCPPP2R1A-like HEAT repeat

HEAT_2aa 378–479UCSCHEAT repeats

HEATaa 494–524UCSCHEAT repeat

Gene Aliases

HGNC Name

protein phosphatase 2 scaffold subunit Abeta

HGNC Alias Symbols

PR65B; PP2A-Abeta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002716.5

p.R549C

c.1645C>T

Surrounding Variants

3 papers

NM_002716.5

p.V545A

c.1634T>C

1 paper

NM_002716.5

p.V545L

c.1633G>T

1 paper

NM_002716.5

p.V545L

c.1633G>C

3 papers

NM_002716.5

p.I559F

c.1675A>T

1 paper

NM_002716.5

p.L538S

c.1613T>C

1 paper

NM_002716.5

p.P535A

c.1603C>G

1 paper

NM_002716.5

p.N566Splc

c.1697+2T>G

1 paper

NM_002716.5

p.N518_A519Splc

c.1555-2A>G

1 paper

NM_002716.5

p.N518_A519Splc

c.1555-38A>T

1 paper

NM_002716.5

p.K578T

c.1733A>C

1 paper

NM_002716.5

p.N518_A519Splc

c.1554+1G>A

1 paper

NM_002716.5

p.T513P

c.1537A>C