Varaico: Literature-Extracted Genetic Variants

PPP2R1B

94 papers

RefSeq Summary

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell grow...

Pfam Domains

2AA_helicalaa 96–285UCSCPhosphatase 2A Regulatory Subunit A, helical domain

PPP2R1A-like_HEATaa 288–369UCSCPPP2R1A-like HEAT repeat

HEAT_2aa 378–479UCSCHEAT repeats

HEATaa 494–524UCSCHEAT repeat

Gene Aliases

HGNC Name

protein phosphatase 2 scaffold subunit Abeta

HGNC Alias Symbols

PR65B; PP2A-Abeta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002716.5

p.L101P

c.302T>C

Surrounding Variants

1 paper

NM_002716.5

p.A98S

c.292G>T

1 paper

NM_002716.5

p.F97L

c.291T>G

1 paper

NM_002716.5

p.F97L

c.291T>A

1 paper

NM_002716.5

p.F97L

c.289T>C

13 papers

NM_002716.5

p.G90D

c.269G>A

1 paper

NM_002716.5

p.E76V

c.227A>T

1 paper

NM_002716.5

p.E76Q

c.226G>C

2 papers

NM_002716.5

p.Y72Y

c.216T>C

1 paper

NM_002716.5

p.D69Splc

c.206-26A>G

6 papers

NM_002716.5

p.P65S

c.193C>T

1 paper

NM_002716.5

p.T49R

c.146C>G

1 paper

NM_002716.5

p.Q38_L39Splc

c.115-95C>A