Varaico: Literature-Extracted Genetic Variants

PPP5C

440 papers

RefSeq Summary

This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphor...

Pfam Domains

TPR_1aa 28–61UCSCTetratricopeptide repeat

PPP5aa 136–228UCSCPPP5 TPR repeat region

Metallophosaa 235–431UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 5 catalytic subunit

HGNC Previous Symbol

PPP5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006247.4

p.Y65*

c.195T>G

Surrounding Variants

1 paper

NM_006247.4

p.Y65*

c.195T>A

1 paper

NM_006247.4

p.I63M

c.189C>G

1 paper

NM_006247.4

p.R68C

c.202C>T

1 paper

NM_006247.4

p.L57insFs

c.170_171insA

7 papers

NM_006247.4

p.T75P

c.223A>C

1 paper

NM_006247.4

p.E56A

c.167A>C

1 paper

NM_006247.4

p.T75delFs

c.225delT

1 paper

NM_006247.4

p.E56insFs

c.166dupG

1 paper

NM_006247.4

p.E76K

c.226G>A

3 papers

NM_006247.4

p.E76A

c.227A>C

2 papers

NM_006247.4

p.I55F

c.163A>T

2 papers

NM_006247.4

p.I55insFs

c.163_164insA