Varaico: Literature-Extracted Genetic Variants

PPP5C

440 papers

RefSeq Summary

This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphor...

Pfam Domains

TPR_1aa 28–61UCSCTetratricopeptide repeat

PPP5aa 136–228UCSCPPP5 TPR repeat region

Metallophosaa 235–431UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 5 catalytic subunit

HGNC Previous Symbol

PPP5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006247.4

p.G184S

c.550G>A

Surrounding Variants

1 paper

NM_006247.4

p.K185R

c.554A>G

1 paper

NM_006247.4

p.E182Q

c.544G>C

1 paper

NM_006247.4

p.V186_T187insFs

c.558_559insC

2 papers

NM_006247.4

p.P179L

c.536C>T

1 paper

NM_006247.4

p.G178R

c.532G>A

1 paper

NM_006247.4

p.G178R

c.532G>C

1 paper

NM_006247.4

p.E175*

c.523G>T

1 paper

NM_006247.4

p.T171Splc

c.512-1G>A

1 paper

NM_006247.4

p.T171Splc

c.512-2A>G

1 paper

NM_006247.4

p.W197L

c.590G>T

1 paper

NM_006247.4

p.K199R

c.596A>G

1 paper

NM_006247.4

p.D200A

c.599A>C