Varaico: Literature-Extracted Genetic Variants

Gene:PPP6C
Variant:p.R264C

PPP6C

125 papers

RefSeq Summary

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pse...

Pfam Domains

Metallophosaa 46–241UCSCCalcineurin-like phosphoesterase
Metallophosaa 46–241UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 6 catalytic subunit

HGNC Alias Symbol

PP6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
31 papers
NM_002721.5
p.R264C
c.790C>T
NM_001123355.2
p.R301C
c.901C>T
Surrounding Variants
1 paper
NM_002721.5
p.G266R
c.796G>C
1 paper
NM_002721.5
p.G266R
c.796G>A
3 papers
NM_002721.5
p.P259S
c.775C>T
6 papers
NM_001123355.2
p.S307L
c.920C>T
NM_002721.5
p.S270L
c.809C>T
1 paper
NM_002721.5
p.W256*
c.768G>A
1 paper
NM_002721.5
p.W256*
c.767G>A
1 paper
NM_002721.5
p.V253M
c.757G>A
1 paper
NM_002721.5
p.L252L
c.754C>T
1 paper
NM_002721.5
p.V277I
c.829G>A
1 paper
NM_002721.5
p.V277E
c.830T>A
1 paper
NM_002721.5
p.E250K
c.748G>A
1 paper
NM_002721.5
p.K245N
c.735A>T
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