Varaico: Literature-Extracted Genetic Variants

Gene:PPP6C
Variant:p.E200K

PPP6C

125 papers

RefSeq Summary

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pse...

Pfam Domains

Metallophosaa 46–241UCSCCalcineurin-like phosphoesterase
Metallophosaa 46–241UCSCCalcineurin-like phosphoesterase

Gene Aliases

HGNC Name

protein phosphatase 6 catalytic subunit

HGNC Alias Symbol

PP6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002721.5
p.E200K
c.598G>A
Surrounding Variants
1 paper
NM_002721.5
p.P199S
c.595C>T
1 paper
NM_002721.5
p.D198insFs
c.592_593insT
1 paper
NM_002721.5
p.V202M
c.604G>A
1 paper
NM_002721.5
p.S197L
c.590C>T
1 paper
NM_002721.5
p.T204I
c.611C>T
1 paper
NM_002721.5
p.T204N
c.611C>A
1 paper
NM_002721.5
p.L194R
c.581T>G
1 paper
NM_002721.5
p.A206ins2
c.616_617ins6
1 paper
NM_002721.5
p.A206T
c.616G>A
1 paper
NM_002721.5
p.D193Y
c.577G>T
1 paper
NM_002721.5
p.C192Y
c.575G>A
1 paper
NM_002721.5
p.C192R
c.574T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."