Varaico: Literature-Extracted Genetic Variants

Gene:PRAM1
Variant:p.K315T

PRAM1

92 papers

RefSeq Summary

The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal...

Pfam Domains

hSH3aa 576–665UCSCHelically-extended SH3 domain

Gene Aliases

HGNC Name

PML-RARA regulated adaptor molecule 1

HGNC Alias Symbol

PML-RAR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_032152.5
p.K315T
c.944A>C
Surrounding Variants
1 paper
NM_032152.5
p.P322L
c.965C>T
2 papers
NM_032152.5
p.E301K
c.901G>A
1 paper
NM_032152.5
p.L290F
c.868C>T
1 paper
NM_032152.5
p.L345P
c.1034T>C
1 paper
NM_032152.5
p.P276R
c.827C>G
1 paper
NM_032152.5
p.R355C
c.1063C>T
1 paper
NM_032152.5
p.R355H
c.1064G>A
1 paper
NM_032152.5
p.A268T
c.802G>A
1 paper
NM_032152.5
p.H369P
c.1106A>C
1 paper
NM_032152.5
p.P257H
c.770C>A
1 paper
NM_032152.5
p.A249V
c.746C>T
1 paper
NM_032152.5
p.E248K
c.742G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."