Varaico: Literature-Extracted Genetic Variants

Gene:PRDX1
Variant:p.C173S

PRDX1

111 papers

RefSeq Summary

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in c...

Pfam Domains

AhpC-TSAaa 8–142UCSCAhpC/TSA family
1-cysPrx_Caa 162–197UCSCC-terminal domain of 1-Cys peroxiredoxin

Gene Aliases

HGNC Name

peroxiredoxin 1

HGNC Previous Symbol

PAGA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_181697.3
p.C173S
c.517T>A
Surrounding Variants
2 papers
NM_181697.3
p.C173S
c.518G>C
8 papers
NM_181697.3
p.V172Splc
c.515-1G>T
6 papers
NM_181697.3
p.V172Splc
c.515-2A>T
1 paper
NM_181697.3
p.P179P
c.537T>G
1 paper
NM_181697.3
p.D182N
c.544G>A
1 paper
NM_181697.3
p.I184M
c.552C>G
1 paper
NM_181697.3
p.Q189*
c.565C>T
1 paper
NM_181697.3
p.Q189K
c.565C>A
1 paper
NM_181697.3
p.Q198H
c.594G>T
1 paper
NM_181697.3
p.Q198H
c.594G>C
1 paper
NM_181697.3
p.Q164L
c.491A>T
1 paper
NM_181697.3
p.Q161E
c.481C>G
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