Varaico: Literature-Extracted Genetic Variants

Gene:PRDX2
Variant:p.T142A

PRDX2

727 papers

RefSeq Summary

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cell...

Pfam Domains

AhpC-TSAaa 8–141UCSCAhpC/TSA family
1-cysPrx_Caa 161–196UCSCC-terminal domain of 1-Cys peroxiredoxin

Gene Aliases

HGNC Name

peroxiredoxin 2

HGNC Previous Symbol

TDPX1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005809.6
p.T142A
c.424A>G
Surrounding Variants
1 paper
NM_005809.6
p.T142T
c.426T>A
1 paper
NM_005809.6
p.I141N
c.422T>A
1 paper
NM_005809.6
p.V143L
c.427G>C
1 paper
NM_005809.6
p.R139H
c.416G>A
1 paper
NM_005809.6
p.R139C
c.415C>T
2 papers
NM_005809.6
p.R139S
c.415C>A
1 paper
NM_005809.6
p.L138L
c.414T>C
1 paper
NM_005809.6
p.L138F
c.412C>T
1 paper
NM_005809.6
p.L138I
c.412C>A
1 paper
NM_005809.6
p.V137V
c.411C>T
1 paper
NM_005809.6
p.P147S
c.439C>T
1 paper
NM_005809.6
p.P147P
c.441T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."