Varaico: Literature-Extracted Genetic Variants

Gene:PRDX6
Variant:p.D85A

PRDX6

103 papers

RefSeq Summary

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation ...

Pfam Domains

AhpC-TSAaa 7–146UCSCAhpC/TSA family
1-cysPrx_Caa 166–205UCSCC-terminal domain of 1-Cys peroxiredoxin

Gene Aliases

HGNC Name

peroxiredoxin 6

HGNC Alias Symbols

AOP2; KIAA0106; 1-Cys; NSGPx; aiPLA2; MGC46173; p29

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004905.3
p.D85A
c.254A>C
Surrounding Variants
1 paper
NM_004905.3
p.D85E
c.255T>A
1 paper
NM_004905.3
p.D85E
c.255T>G
3 papers
NM_004905.3
p.C91S
c.271T>A
3 papers
NM_004905.3
p.C91S
c.272G>C
1 paper
NM_004905.3
p.E96D
c.288A>C
1 paper
NM_004905.3
p.E96D
c.288A>T
1 paper
NM_004905.3
p.I102M
c.306C>G
1 paper
NM_004905.3
p.R108P
c.323G>C
1 paper
NM_004905.3
p.R108R
c.324G>A
1 paper
NM_004905.3
p.A111D
c.332C>A
1 paper
NM_004905.3
p.L117L
c.349C>T
1 paper
NM_004905.3
p.D118V
c.353A>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."