Varaico: Literature-Extracted Genetic Variants

Gene:PRDX6
Variant:p.Y217*

PRDX6

103 papers

RefSeq Summary

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation ...

Pfam Domains

AhpC-TSAaa 7–146UCSCAhpC/TSA family
1-cysPrx_Caa 166–205UCSCC-terminal domain of 1-Cys peroxiredoxin

Gene Aliases

HGNC Name

peroxiredoxin 6

HGNC Alias Symbols

AOP2; KIAA0106; 1-Cys; NSGPx; aiPLA2; MGC46173; p29

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_004905.3
p.Y217*
c.651C>A
Surrounding Variants
2 papers
NM_004905.3
p.Y217*
c.651C>G
1 paper
NM_004905.3
p.K215E
c.643A>G
1 paper
NM_004905.3
p.K215_T221del0
c.643_663del21
1 paper
NM_004905.3
p.G214delFs
c.641delG
1 paper
NM_004905.3
p.E210E
c.630G>A
1 paper
NM_004905.3
p.*225Q
c.673T>C
1 paper
NM_004905.3
p.V206delFs
c.618delC
1 paper
NM_004905.3
p.G205*
c.613G>T
1 paper
NM_004905.3
p.P203P
c.609G>A
1 paper
NM_004905.3
p.K204delFs
c.612delA
1 paper
NM_004905.3
p.P203L
c.608C>T
1 paper
NM_004905.3
p.F202insFs
c.605dupT
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."