Varaico: Literature-Extracted Genetic Variants

PRIM2

94 papers

RefSeq Summary

This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This hetero...

Pfam Domains

DNA_primase_lrg_Naa 30–239UCSCEukaryotic and archaeal DNA primase, large subunit N-terminal domain

DNA_primase_lrgaa 277–448UCSCEukaryotic and archaeal DNA primase, large subunit C-terminal domain

Gene Aliases

HGNC Name

DNA primase subunit 2

HGNC Previous Symbol

PRIM2A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000947.5

p.S182S

c.546C>G

Surrounding Variants

4 papers

NM_000947.5

p.E181K

c.541G>A

1 paper

NM_000947.5

p.E157G

c.470A>G

1 paper

NM_000947.5

p.L202S

c.605T>C

6 papers

NM_000947.5

p.D204G

c.611A>G