Varaico: Literature-Extracted Genetic Variants

PRKAA2

844 papers

RefSeq Summary

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma su...

Pfam Domains

Pkinaseaa 16–268UCSCProtein kinase domain

AMPK_alpha_AIDaa 288–333UCSCAMP-activated protein kinase, alpha subunit, autoinhibitory domain

AdenylateSensoraa 401–495UCSCAdenylate sensor of SNF1-like protein kinase

Gene Aliases

HGNC Name

protein kinase AMP-activated catalytic subunit alpha 2

HGNC Alias Symbols

AMPK; AMPKa2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006252.4

p.K6R

c.17A>G

Surrounding Variants

1 paper

NM_006252.4

p.K6Q

c.16A>C

1 paper

NM_006252.4

p.H7insFs

c.19dupC

1 paper

NM_006252.4

p.H7Y

c.19C>T

1 paper

NM_006252.4

p.Q5*

c.13C>T

1 paper

NM_006252.4

p.K4K

c.12G>A

5 papers

NM_006252.4

p.K4N

c.12G>C

1 paper

NM_006252.4

p.K4Q

c.10A>C

1 paper

NM_006252.4

p.D8E

c.24C>A

1 paper

NM_006252.4

p.G9insFs

c.27dupG

1 paper

NM_006252.4

p.D8E

c.24C>G

1 paper

NM_006252.4

p.G9W

c.25G>T

1 paper

NM_006252.4

p.G9G

c.27G>A