Varaico: Literature-Extracted Genetic Variants

Gene:PRKACA
Variant:p.S264C

PRKACA

234 papers

RefSeq Summary

This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes ...

Pfam Domains

Pkinaseaa 44–298UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cAMP-activated catalytic subunit alpha

HGNC Alias Symbol

PKACa

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002730.4
p.S264C
c.791C>G
Surrounding Variants
1 paper
NM_002730.4
p.S263C
c.787A>T
1 paper
NM_002730.4
p.L266V
c.796T>G
1 paper
NM_002730.4
p.R271W
c.811C>T
1 paper
NM_002730.4
p.R257C
c.769C>T
1 paper
NM_002730.4
p.F282C
c.845T>G
1 paper
NM_002730.4
p.K286del1
c.856_857delCTT
13 papers
NM_002730.4
p.H295R
c.884A>G
3 papers
NM_002730.4
p.A299V
c.896C>T
1 paper
NM_002730.4
p.I306T
c.917T>C
1 paper
NM_002730.4
p.F315Y
c.944T>A
1 paper
NM_002730.4
p.G323V
c.968G>T
1 paper
NM_002730.4
p.T325K
c.974C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."