Varaico: Literature-Extracted Genetic Variants

Gene:PRKACA
Variant:p.L28F

PRKACA

234 papers

RefSeq Summary

This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes ...

Pfam Domains

Pkinaseaa 44–298UCSCProtein kinase domain

Gene Aliases

HGNC Name

protein kinase cAMP-activated catalytic subunit alpha

HGNC Alias Symbol

PKACa

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_002730.4
p.L28F
c.82C>T
Surrounding Variants
1 paper
NM_002730.4
p.K29R
c.86A>G
1 paper
NM_002730.4
p.K30E
c.88A>G
8 papers
NM_002730.4
p.E32V
c.95A>T
2 papers
NM_002730.4
p.S33C
c.97A>T
1 paper
NM_002730.4
p.P34L
c.101C>T
1 paper
NM_002730.4
p.F19C
c.56T>G
1 paper
NM_002730.4
p.E18V
c.53A>T
1 paper
NM_002730.4
p.V16Splc
c.47-270T>C
1 paper
NM_002730.4
p.H40Y
c.118C>T
1 paper
NM_002730.4
p.K48R
c.143A>G
2 papers
NM_002730.4
p.T49I
c.146C>T
1 paper
NM_002730.4
p.T52M
c.155C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."