Varaico: Literature-Extracted Genetic Variants

PRKAR1A

551 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 25–62UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 155–238UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 273–360UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type I regulatory subunit alpha

HGNC Previous Symbols

PRKAR1; TSE1; PKR1; Prkar1alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002734.5

p.M1_G4del4

c.1_11del12

Surrounding Variants

1 paper

NM_002734.5

p.M1_E2delFs

c.1_4del4

2 papers

NM_002734.5

p.M1insFs

c.1_2insG

30 papers

NM_002734.5

p.M1V

c.1A>G

1 paper

NM_002734.5

p.M1Fs

c.2delinsCTGFs

1 paper

NM_002734.5

p.M1insFs

c.2_3insG

1 paper

NM_002734.5

p.M1insFs

c.2_3insGC

2 papers

NM_002734.5

p.E2delFs

c.4delG

6 papers

NM_002734.5

p.M1I

c.3G>A

1 paper

NM_002734.5

p.M1_E2insFs

c.3_4insA

2 papers

NM_002734.5

p.M1I

c.3G>T

1 paper

NM_002734.5

p.E2_S5delFs

c.4_13del10

1 paper

NM_002734.5

p.E2insFs

c.5dupA