Varaico: Literature-Extracted Genetic Variants

PRKAR1A

551 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 25–62UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 155–238UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 273–360UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type I regulatory subunit alpha

HGNC Previous Symbols

PRKAR1; TSE1; PKR1; Prkar1alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002734.5

p.S5insFs

c.15dupT

Surrounding Variants

3 papers

NM_002734.5

p.T6delFs

c.18delC

1 paper

NM_002734.5

p.G4G

c.12C>T

1 paper

NM_002734.5

p.T6I

c.17C>T

3 papers

NM_002734.5

p.T6T

c.18C>G

1 paper

NM_002734.5

p.T6T

c.18C>T

1 paper

NM_002734.5

p.G4insFs

c.10_11insGT

2 papers

NM_002734.5

p.G4fs

c.10_11fs

1 paper

NM_002734.5

p.A7T

c.19G>A

1 paper

NM_002734.5

p.A7fs

c.19_20fs

1 paper

NM_002734.5

p.A7delFs

c.21delC

1 paper

NM_002734.5

p.G4delFs

c.11delG

3 papers

NM_002734.5

p.S3insFs

c.8_9insT