Varaico: Literature-Extracted Genetic Variants

PRKAR1A

551 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 25–62UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 155–238UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 273–360UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type I regulatory subunit alpha

HGNC Previous Symbols

PRKAR1; TSE1; PKR1; Prkar1alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002734.5

p.V156delFs

c.466delG

Surrounding Variants

1 paper

NM_002734.5

p.S155fs

c.463_464fs

2 papers

NM_002734.5

p.S155delFs

c.463delT

1 paper

NM_002734.5

p.S157F

c.470C>T

1 paper

NM_002734.5

p.M153delFs

c.457delA

1 paper

NM_002734.5

p.D151delFs

c.453delT

1 paper

NM_002734.5

p.A160delFs

c.478delG

1 paper

NM_002734.5

p.A160P

c.478G>C

1 paper

NM_002734.5

p.A160fs

c.478_479fs

1 paper

NM_002734.5

p.G161delFs

c.482delG

2 papers

NM_002734.5

p.G161fs

c.481_482fs

1 paper

NM_002734.5

p.G161E

c.482G>A

3 papers

NM_002734.5

p.I149T

c.446T>C