Varaico: Literature-Extracted Genetic Variants

PRKAR1A

551 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 25–62UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 155–238UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 273–360UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type I regulatory subunit alpha

HGNC Previous Symbols

PRKAR1; TSE1; PKR1; Prkar1alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

36 papers

NM_002734.5

p.V164delFs

c.491_492delTG

Surrounding Variants

2 papers

NM_002734.5

p.T163delFs

c.488delC

1 paper

NM_002734.5

p.T163T

c.489T>C

5 papers

NM_002734.5

p.V164fs

c.490_491fs

1 paper

NM_002734.5

p.T163delFs

c.487_488delAC

6 papers

NM_002734.5

p.V164fs

c.490_491fs

1 paper

NM_002734.5

p.V164E

c.491T>A

2 papers

NM_002734.5

p.V164V

c.492G>A

1 paper

NM_002734.5

p.E162_T163insG

c.484_488ins3

1 paper

NM_002734.5

p.I165insFs

c.494dupT

1 paper

NM_002734.5

p.I165fs

c.493_494fs

1 paper

NM_002734.5

p.G161E

c.482G>A

2 papers

NM_002734.5

p.G161fs

c.481_482fs