Varaico: Literature-Extracted Genetic Variants

PRKAR1A

551 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 25–62UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 155–238UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 273–360UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type I regulatory subunit alpha

HGNC Previous Symbols

PRKAR1; TSE1; PKR1; Prkar1alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002734.5

p.A213A

c.639C>G

Surrounding Variants

1 paper

NM_002734.5

p.T214delFs

c.641delC

1 paper

NM_002734.5

p.T214fs

c.640_641fs

16 papers

NM_002734.5

p.A213D

c.638C>A

2 papers

NM_002734.5

p.T214insFs

c.642dupT

5 papers

NM_002734.5

p.A213T

c.637G>A

1 paper

NM_002734.5

p.A213fs

c.637_638fs

1 paper

NM_002734.5

p.A213delFs

c.637delG

1 paper

NM_002734.5

p.V215F

c.643G>T

1 paper

NM_002734.5

p.A212P

c.634G>C

1 paper

NM_002734.5

p.R211S

c.633A>C

1 paper

NM_002734.5

p.R211R

c.633A>G

1 paper

NM_002734.5

p.R211S

c.633A>T