Varaico: Literature-Extracted Genetic Variants

PRKAR1A

551 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 25–62UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 155–238UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 273–360UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type I regulatory subunit alpha

HGNC Previous Symbols

PRKAR1; TSE1; PKR1; Prkar1alpha

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002734.5

p.W262_E263delins

c.786_787delinsCT

Surrounding Variants

1 paper

NM_002734.5

p.W262*

c.786G>A

1 paper

NM_002734.5

p.W262C

c.786G>C

1 paper

NM_002734.5

p.W262C

c.786G>T

1 paper

NM_002734.5

p.W262_E263Fs

c.786_787delinsCFs

1 paper

NM_002734.5

p.W262*

c.785G>A

1 paper

NM_002734.5

p.E263fs

c.787_788fs

1 paper

NM_002734.5

p.E263delFs

c.787delG

1 paper

NM_002734.5

p.K261delFs

c.783delG

1 paper

NM_002734.5

p.K261fs

c.781_782fs

3 papers

NM_002734.5

p.K261insFs

c.781_782insT

1 paper

NM_002734.5

p.K261*

c.781A>T

1 paper

NM_002734.5

p.R264H

c.791G>A