Varaico: Literature-Extracted Genetic Variants

PRKAR2A

56 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 8–45UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 157–244UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 279–373UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type II regulatory subunit alpha

HGNC Previous Symbol

PRKAR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004157.4

p.F336Y

c.1007T>A

Surrounding Variants

1 paper

NM_004157.4

p.Q334*

c.1000C>T

1 paper

NM_004157.4

p.R329C

c.985C>T

2 papers

NM_004157.4

p.N344D

c.1030A>G

1 paper

NM_004157.4

p.R347I

c.1040G>T

1 paper

NM_004157.4

p.R347T

c.1040G>C

1 paper

NM_004157.4

p.R347K

c.1040G>A

1 paper

NM_004157.4

p.A349V

c.1046C>T

1 paper

NM_004157.4

p.Q323P

c.968A>C

1 paper

NM_004157.4

p.D356V

c.1067A>T

1 paper

NM_004157.4

p.K358N

c.1074A>C

1 paper

NM_004157.4

p.V397M

c.1189G>A

1 paper

NM_004157.4

p.I310V

c.928A>G