Varaico: Literature-Extracted Genetic Variants

PRKAR2A

56 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 8–45UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 157–244UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 279–373UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type II regulatory subunit alpha

HGNC Previous Symbol

PRKAR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004157.4

p.R203C

c.607C>T

Surrounding Variants

1 paper

NM_004157.4

p.D201N

c.601G>A

1 paper

NM_004157.4

p.S205C

c.613A>T

1 paper

NM_004157.4

p.F206C

c.617T>G

1 paper

NM_004157.4

p.Q199*

c.595C>T

1 paper

NM_004157.4

p.G198D

c.593G>A

2 papers

NM_004157.4

p.R195H

c.584G>A

1 paper

NM_004157.4

p.Q193delFs

c.578delT

1 paper

NM_004157.4

p.Y213H

c.637T>C

1 paper

NM_004157.4

p.N192S

c.575A>G

1 paper

NM_004157.4

p.P216L

c.647C>T

1 paper

NM_004157.4

p.W230*

c.690G>A

1 paper

NM_004157.4

p.L232Q

c.695T>A