Varaico: Literature-Extracted Genetic Variants

PRKAR2A

56 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 8–45UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 157–244UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 279–373UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type II regulatory subunit alpha

HGNC Previous Symbol

PRKAR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004157.4

p.L40L

c.118C>T

Surrounding Variants

1 paper

NM_004157.4

p.P46Q

c.137C>A

1 paper

NM_004157.4

p.P46P

c.138A>G

1 paper

NM_004157.4

p.A47G

c.140C>G

1 paper

NM_004157.4

p.A53T

c.157G>A

1 paper

NM_004157.4

p.L50_P51delFs

c.150_153del4

1 paper

NM_004157.4

p.G60S

c.178G>A

1 paper

NM_004157.4

p.H61H

c.183C>T

1 paper

NM_004157.4

p.M1V

c.1A>G

1 paper

NM_004157.4

p.E87A

c.260A>C