Varaico: Literature-Extracted Genetic Variants

PRKAR2B

55 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 7–44UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 172–259UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 294–387UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type II regulatory subunit beta

HGNC Previous Symbol

PRKAR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002736.3

p.Q34L

c.101A>T

Surrounding Variants

2 papers

NM_002736.3

p.A32A

c.96G>T

1 paper

NM_002736.3

p.L28L

c.82C>T

1 paper

NM_002736.3

p.Q24H

c.72G>C

1 paper

NM_002736.3

p.G47D

c.140G>A

1 paper

NM_002736.3

p.R50_F51delFs

c.150_153del4

1 paper

NM_002736.3

p.L12V

c.34C>G

1 paper

NM_002736.3

p.D60N

c.178G>A

1 paper

NM_002736.3

p.A7A

c.21G>A

2 papers

NM_002736.3

p.M1V

c.1A>G