Varaico: Literature-Extracted Genetic Variants

PRKAR2B

55 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 7–44UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 172–259UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 294–387UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type II regulatory subunit beta

HGNC Previous Symbol

PRKAR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002736.3

p.Q165H

c.495A>C

Surrounding Variants

1 paper

NM_002736.3

p.D168N

c.502G>A

1 paper

NM_002736.3

p.D183Y

c.547G>T

1 paper

NM_002736.3

p.D189_N190delFs

c.565_568del4

1 paper

NM_002736.3

p.V193delFs

c.578delT

1 paper

NM_002736.3

p.R196I

c.587G>T

1 paper

NM_002736.3

p.K204_D206delFs

c.611_617del7

1 paper

NM_002736.3

p.D216H

c.646G>C

1 paper

NM_002736.3

p.D216G

c.647A>G

1 paper

NM_002736.3

p.R218C

c.652C>T

1 paper

NM_002736.3

p.E223K

c.667G>A

1 paper

NM_002736.3

p.A234T

c.700G>A

1 paper

NM_002736.3

p.I236T

c.707T>C