Varaico: Literature-Extracted Genetic Variants

PRKAR2B

55 papers

RefSeq Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation...

Pfam Domains

RIIaaa 7–44UCSCRegulatory subunit of type II PKA R-subunit

cNMP_bindingaa 172–259UCSCCyclic nucleotide-binding domain

cNMP_bindingaa 294–387UCSCCyclic nucleotide-binding domain

Gene Aliases

HGNC Name

protein kinase cAMP-dependent type II regulatory subunit beta

HGNC Previous Symbol

PRKAR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002736.3

p.Y297H

c.889T>C

Surrounding Variants

1 paper

NM_002736.3

p.R285H

c.854G>A

1 paper

NM_002736.3

p.R285C

c.853C>T

1 paper

NM_002736.3

p.L274L

c.822G>A

1 paper

NM_002736.3

p.M266I

c.798G>A

1 paper

NM_002736.3

p.M266I

c.798G>C

1 paper

NM_002736.3

p.M266I

c.798G>T

1 paper

NM_002736.3

p.K263delFs

c.788delA

1 paper

NM_002736.3

p.I256T

c.767T>C

1 paper

NM_002736.3

p.G307*

c.919G>T

1 paper

NM_002736.3

p.A310S

c.928G>T

1 paper

NM_002736.3

p.I315V

c.943A>G

1 paper

NM_002736.3

p.E317Q

c.949G>C