Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

1–12 of 327 variants

19 papers

NM_006254.4

p.G510S

c.1528G>A

10 papers

NM_006254.4

p.G248S

c.742G>A

8 papers

NM_006254.4

p.R614W

c.1840C>T

7 papers

NM_006254.4

p.T451Splc

c.1352+1G>A

6 papers

NM_006254.4

p.G432W

c.1294G>T

4 papers

NM_006254.4

p.Y155F

c.464A>T

4 papers

NM_006254.4

p.N431_G432insFs

c.1293_1294insA

4 papers

NM_006254.4

p.T594T

c.1782C>G

3 papers

NM_006254.4

p.R67C

c.199C>T

3 papers

NM_006254.4

p.Q191*

c.571C>T

3 papers

NM_006254.4

p.P230L

c.689C>T

3 papers

NM_006254.4

p.D263Splc

c.788-2A>G