Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.G66fs

c.196_197fs

Surrounding Variants

1 paper

NM_006254.4

p.G66fs

c.196_197fs

1 paper

NM_006254.4

p.G66E

c.197G>A

1 paper

NM_006254.4

p.G66A

c.197G>C

1 paper

NM_006254.4

p.R67S

c.199C>A

3 papers

NM_006254.4

p.R67C

c.199C>T

2 papers

NM_006254.4

p.Y64F

c.191A>T

1 paper

NM_006254.4

p.V68I

c.202G>A

1 paper

NM_006254.4

p.Y64D

c.190T>G

1 paper

NM_006254.4

p.I69T

c.206T>C

2 papers

NM_006254.4

p.H62D

c.184C>G

1 paper

NM_006254.4

p.Q70Q

c.210G>A

1 paper

NM_006254.4

p.D60D

c.180T>C