Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.R94G

c.280C>G

Surrounding Variants

1 paper

NM_006254.4

p.R94S

c.280C>A

1 paper

NM_006254.4

p.E93K

c.277G>A

2 papers

NM_006254.4

p.C95*

c.285C>A

1 paper

NM_006254.4

p.V90M

c.268G>A

1 paper

NM_006254.4

p.S89*

c.266C>A

1 paper

NM_006254.4

p.N99K

c.297T>A

1 paper

NM_006254.4

p.N99K

c.297T>G

1 paper

NM_006254.4

p.E103*

c.307G>T

1 paper

NM_006254.4

p.V84M

c.250G>A

1 paper

NM_006254.4

p.E79D

c.237G>C

1 paper

NM_006254.4

p.E79insFs

c.236dupA

1 paper

NM_006254.4

p.E79fs

c.235_236fs