Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.F165L

c.493T>C

Surrounding Variants

1 paper

NM_006254.4

p.F165L

c.495C>A

1 paper

NM_006254.4

p.F165L

c.495C>G

2 papers

NM_006254.4

p.A163T

c.487G>A

1 paper

NM_006254.4

p.G167V

c.500G>T

1 paper

NM_006254.4

p.P169H

c.506C>A

2 papers

NM_006254.4

p.T170I

c.509C>T

1 paper

NM_006254.4

p.C172Y

c.515G>A

4 papers

NM_006254.4

p.Y155F

c.464A>T

1 paper

NM_006254.4

p.Y155D

c.463T>G

1 paper

NM_006254.4

p.V179A

c.536T>C

1 paper

NM_006254.4

p.A147D

c.440C>A

1 paper

NM_006254.4

p.G146E

c.437G>A