Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006254.4

p.Q191*

c.571C>T

Surrounding Variants

1 paper

NM_006254.4

p.Q191insFs

c.571_572ins25

1 paper

NM_006254.4

p.Q191insFs

c.571_572ins29

1 paper

NM_006254.4

p.C189Y

c.566G>A

1 paper

NM_006254.4

p.C189R

c.565T>C

1 paper

NM_006254.4

p.Y187C

c.560A>G

1 paper

NM_006254.4

p.Y187F

c.560A>T

1 paper

NM_006254.4

p.N183K

c.549C>A

1 paper

NM_006254.4

p.N183K

c.549C>G

1 paper

NM_006254.4

p.Q191Splc

c.571+51G>A

1 paper

NM_006254.4

p.V179A

c.536T>C

1 paper

NM_006254.4

p.C172Y

c.515G>A

2 papers

NM_006254.4

p.T170I

c.509C>T