Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_006254.4

p.D263Splc

c.788-2A>G

Surrounding Variants

1 paper

NM_006254.4

p.D263_K275delFs

c.788_825del38

1 paper

NM_006254.4

p.D263fs

c.787_788fs

1 paper

NM_006254.4

p.M266I

c.798G>A

1 paper

NM_006254.4

p.M266I

c.798G>C

1 paper

NM_006254.4

p.M266I

c.798G>T

1 paper

NM_006254.4

p.R273W

c.817C>T

1 paper

NM_006254.4

p.V276L

c.826G>C

1 paper

NM_006254.4

p.V276L

c.826G>T

1 paper

NM_006254.4

p.C280C

c.840C>T

1 paper

NM_006254.4

p.A290S

c.868G>T

1 paper

NM_006254.4

p.L291F

c.873G>C

1 paper

NM_006254.4

p.L291F

c.873G>T