Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.M436L

c.1306A>T

Surrounding Variants

1 paper

NM_006254.4

p.M436L

c.1306A>C

1 paper

NM_006254.4

p.M436I

c.1308G>A

1 paper

NM_006254.4

p.M436I

c.1308G>C

1 paper

NM_006254.4

p.M436I

c.1308G>T

1 paper

NM_006254.4

p.D434E

c.1302C>A

1 paper

NM_006254.4

p.D434E

c.1302C>G

1 paper

NM_006254.4

p.D434fs

c.1300_1301fs

1 paper

NM_006254.4

p.H438R

c.1313A>G

1 paper

NM_006254.4

p.G432A

c.1295G>C

1 paper

NM_006254.4

p.G432R

c.1294G>A

1 paper

NM_006254.4

p.G432R

c.1294G>C

2 papers

NM_006254.4

p.G432fs

c.1294_1295fs