Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.R449H

c.1346G>A

Surrounding Variants

1 paper

NM_006254.4

p.R449P

c.1346G>C

2 papers

NM_006254.4

p.R449C

c.1345C>T

2 papers

NM_006254.4

p.A450T

c.1348G>A

1 paper

NM_006254.4

p.T451insFs

c.1352_1353ins4

7 papers

NM_006254.4

p.T451Splc

c.1352+1G>A

2 papers

NM_006254.4

p.T451Splc

c.1352+4C>T

1 paper

NM_006254.4

p.F445Y

c.1334T>A

1 paper

NM_006254.4

p.D441N

c.1321G>A

1 paper

NM_006254.4

p.H438R

c.1313A>G

1 paper

NM_006254.4

p.M436I

c.1308G>A

1 paper

NM_006254.4

p.M436I

c.1308G>C

1 paper

NM_006254.4

p.M436I

c.1308G>T