Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.E497V

c.1490A>T

Surrounding Variants

1 paper

NM_006254.4

p.E497K

c.1489G>A

1 paper

NM_006254.4

p.E497D

c.1491G>C

1 paper

NM_006254.4

p.E497D

c.1491G>T

1 paper

NM_006254.4

p.M494R

c.1481T>G

1 paper

NM_006254.4

p.M494V

c.1480A>G

2 papers

NM_006254.4

p.G501W

c.1501G>T

1 paper

NM_006254.4

p.F492L

c.1476T>A

1 paper

NM_006254.4

p.F492F

c.1476T>C

1 paper

NM_006254.4

p.F492L

c.1476T>G

1 paper

NM_006254.4

p.F492L

c.1474T>C

1 paper

NM_006254.4

p.D491A

c.1472A>C

1 paper

NM_006254.4

p.A490V

c.1469C>T