Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.G510V

c.1529G>T

Surrounding Variants

1 paper

NM_006254.4

p.G510D

c.1529G>A

19 papers

NM_006254.4

p.G510S

c.1528G>A

1 paper

NM_006254.4

p.T511P

c.1531A>C

1 paper

NM_006254.4

p.C509R

c.1525T>C

1 paper

NM_006254.4

p.P512L

c.1535C>T

2 papers

NM_006254.4

p.F508del1

c.1522_1523delTTC

2 papers

NM_006254.4

p.T507A

c.1519A>G

1 paper

NM_006254.4

p.D513E

c.1539C>A

1 paper

NM_006254.4

p.D513E

c.1539C>G

2 papers

NM_006254.4

p.A516T

c.1546G>A

1 paper

NM_006254.4

p.R504Q

c.1511G>A

1 paper

NM_006254.4

p.P517L

c.1550C>T