Varaico: Literature-Extracted Genetic Variants

PRKCD

259 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor su...

Pfam Domains

PKC_C2aa 4–112UCSCProtein kinase C delta/epsilon/eta/theta, C2 domain

C1_1aa 159–211UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 231–283UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 349–603UCSCProtein kinase domain

Pkinase_Caa 624–665UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C delta

HGNC Previous Name

protein kinase C, delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006254.4

p.R569H

c.1706G>A

Surrounding Variants

1 paper

NM_006254.4

p.R569G

c.1705C>G

2 papers

NM_006254.4

p.T564M

c.1691C>T

1 paper

NM_006254.4

p.T564S

c.1690A>T

1 paper

NM_006254.4

p.S575P

c.1723T>C

1 paper

NM_006254.4

p.K576insFs

c.1726dupA

1 paper

NM_001354676.2

p.S594S

c.1782C>G

1 paper

NM_006254.4

p.R561S

c.1681C>A

1 paper

NM_006254.4

p.I560T

c.1679T>C

1 paper

NM_001354678.2

p.I594M

c.1782C>G

2 papers

NM_006254.4

p.K581_L582Splc

c.1743+8C>T

1 paper

NM_006254.4

p.K581_L582Splc

c.1743+29T>G

1 paper

NM_006254.4

p.G544D

c.1631G>A