Varaico: Literature-Extracted Genetic Variants

PRKCE

136 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

C2aa 6–119UCSCC2 domain

C1_1aa 170–223UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 243–295UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 408–668UCSCProtein kinase domain

Pkinase_Caa 689–730UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C epsilon

HGNC Previous Name

protein kinase C, epsilon

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005400.3

p.V3L

c.7G>C

Surrounding Variants

1 paper

NM_005400.3

p.V2insFs

c.4_5ins10

1 paper

NM_005400.3

p.G6A

c.17G>C

1 paper

NM_005400.3

p.L7V

c.19C>G

1 paper

NM_005400.3

p.I12I

c.36C>A

2 papers

NM_005400.3

p.E14K

c.40G>A

1 paper

NM_005400.3

p.E14E

c.42G>A

1 paper

NM_005400.3

p.L25P

c.74T>C

1 paper

NM_005400.3

p.D39H

c.115G>C

1 paper

NM_005400.3

p.G52V

c.155G>T

1 paper

NM_005400.3

p.P63Q

c.188C>A

1 paper

NM_005400.3

p.N97Y

c.289A>T

1 paper

NM_005400.3

p.T99P

c.295A>C