Varaico: Literature-Extracted Genetic Variants

PRKCE

136 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

C2aa 6–119UCSCC2 domain

C1_1aa 170–223UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 243–295UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 408–668UCSCProtein kinase domain

Pkinase_Caa 689–730UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C epsilon

HGNC Previous Name

protein kinase C, epsilon

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005400.3

p.P229H

c.686C>A

Surrounding Variants

1 paper

NM_005400.3

p.T218T

c.654A>T

1 paper

NM_005400.3

p.Q197P

c.590A>C

1 paper

NM_005400.3

p.W191Splc

c.573-26T>A

1 paper

NM_005400.3

p.F189Y

c.566T>A

1 paper

NM_005400.3

p.N168N

c.504C>T

1 paper

NM_005400.3

p.V164G

c.491T>G

1 paper

NM_005400.3

p.A159V

c.476C>T

1 paper

NM_005400.3

p.R156G

c.466C>G

1 paper

NM_005400.3

p.R150H

c.449G>A

1 paper

NM_005400.3

p.E149K

c.445G>A

1 paper

NM_005400.3

p.F147delFs

c.439delT

1 paper

NM_005400.3

p.E143K

c.427G>A