Varaico: Literature-Extracted Genetic Variants

PRKCE

136 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide v...

Pfam Domains

C2aa 6–119UCSCC2 domain

C1_1aa 170–223UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 243–295UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 408–668UCSCProtein kinase domain

Pkinase_Caa 689–730UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C epsilon

HGNC Previous Name

protein kinase C, epsilon

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005400.3

p.G233R

c.697G>C

Surrounding Variants

1 paper

NM_005400.3

p.S234A

c.700T>G

1 paper

NM_005400.3

p.Q235Q

c.705G>A

1 paper

NM_005400.3

p.Q235H

c.705G>C

1 paper

NM_005400.3

p.Q235H

c.705G>T

1 paper

NM_005400.3

p.R236Q

c.707G>A

1 paper

NM_005400.3

p.P242T

c.724C>A

1 paper

NM_005400.3

p.Q231_V232Splc

c.694-32G>A

2 papers

NM_005400.3

p.R268W

c.802C>T

1 paper

NM_005400.3

p.Q272R

c.815A>G

1 paper

NM_005400.3

p.P229H

c.686C>A

1 paper

NM_005400.3

p.T218T

c.654A>T

1 paper

NM_005400.3

p.Q197P

c.590A>C