Varaico: Literature-Extracted Genetic Variants

PRKCG

309 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide varie...

Pfam Domains

C1_1aa 36–88UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 101–153UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C2aa 171–277UCSCC2 domain

Pkinaseaa 351–613UCSCProtein kinase domain

Pkinase_Caa 640–675UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C gamma

HGNC Previous Symbols

PKCG; SCA14

Papers

RefSeq ID

Protein change

DNA change

1–12 of 299 variants

38 papers

NM_002739.5

p.G128D

c.383G>A

37 papers

NM_002739.5

p.H101Y

c.301C>T

37 papers

NM_002739.5

p.S119P

c.355T>C

36 papers

NM_002739.5

p.G118D

c.353G>A

29 papers

NM_002739.5

p.S361G

c.1081A>G

28 papers

NM_002739.5

p.V138E

c.413T>A

24 papers

NM_002739.5

p.Q127R

c.380A>G

24 papers

NM_002739.5

p.F643L

c.1927T>C

24 papers

NM_002739.5

p.F643L

c.1929T>A

24 papers

NM_002739.5

p.F643L

c.1929T>G

23 papers

NM_002739.5

p.C150F

c.449G>T

22 papers

NM_002739.5

p.H101Q

c.303C>A