Varaico: Literature-Extracted Genetic Variants

PRKCG

309 papers

RefSeq Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide varie...

Pfam Domains

C1_1aa 36–88UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C1_1aa 101–153UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

C2aa 171–277UCSCC2 domain

Pkinaseaa 351–613UCSCProtein kinase domain

Pkinase_Caa 640–675UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C gamma

HGNC Previous Symbols

PKCG; SCA14

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002739.5

p.S326fs

c.976_977fs

Surrounding Variants

1 paper

NM_002739.5

p.P325insFs

c.975dupC

1 paper

NM_002739.5

p.S328Y

c.983C>A

1 paper

NM_002739.5

p.D333N

c.997G>A

1 paper

NM_002739.5

p.P334H

c.1001C>A

1 paper

NM_002739.5

p.K335R

c.1004A>G

1 paper

NM_002739.5

p.R336L

c.1007G>T

1 paper

NM_002739.5

p.F339F

c.1017C>T

1 paper

NM_002739.5

p.R345C

c.1033C>T

1 paper

NM_002739.5

p.S349T

c.1045T>A

1 paper

NM_002739.5

p.L354H

c.1061T>A

1 paper

NM_002739.5

p.L354L

c.1062C>G

1 paper

NM_002739.5

p.M355I

c.1065G>A