Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

1–12 of 245 variants

14 papers

NM_002740.6

p.R480C

c.1438C>T

5 papers

NM_002740.6

p.Q4H

c.12G>C

5 papers

NM_002740.6

p.R130C

c.388C>T

5 papers

NM_002740.6

p.V216_Y219del0

c.647_655del9

5 papers

NM_002740.6

p.L273delFs

c.819delA

4 papers

NM_002740.6

p.G34W

c.100G>T

4 papers

NM_002740.6

p.R130H

c.389G>A

4 papers

NM_002740.6

p.Y219C

c.656A>G

4 papers

NM_002740.6

p.D396E

c.1188C>A

4 papers

NM_002740.6

p.D396E

c.1188C>G

4 papers

NM_002740.6

p.G581V

c.1742G>T

3 papers

NM_002740.6

p.F66Y

c.197T>A