Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002740.6

p.G20E

c.59G>A

Surrounding Variants

1 paper

NM_002740.6

p.G18V

c.53G>T

1 paper

NM_002740.6

p.G16C

c.46G>T

1 paper

NM_002740.6

p.A15S

c.43G>T

1 paper

NM_002740.6

p.V26I

c.76G>A

1 paper

NM_002740.6

p.R27insFs

c.79dupC

1 paper

NM_002740.6

p.R27fs

c.79_80fs

1 paper

NM_002740.6

p.R27P

c.80G>C

1 paper

NM_002740.6

p.M10I

c.30G>A

1 paper

NM_002740.6

p.M10I

c.30G>C

1 paper

NM_002740.6

p.A30P

c.88G>C

1 paper

NM_002740.6

p.M10I

c.30G>T

2 papers

NM_002740.6

p.Y31C

c.92A>G