Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002740.6

p.D61V

c.182A>T

Surrounding Variants

2 papers

NM_002740.6

p.E63K

c.187G>A

1 paper

NM_002740.6

p.Q64E

c.190C>G

1 paper

NM_002740.6

p.L65R

c.194T>G

2 papers

NM_002740.6

p.D56G

c.167A>G

3 papers

NM_002740.6

p.F66Y

c.197T>A

1 paper

NM_002740.6

p.R55Q

c.164G>A

1 paper

NM_002740.6

p.N52S

c.155A>G

1 paper

NM_002740.6

p.D72_E73delFs

c.216_219del4

1 paper

NM_002740.6

p.G75Splc

c.223+3G>A

1 paper

NM_002740.6

p.I38M

c.114A>G