Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002740.6

p.R126H

c.377G>A

Surrounding Variants

2 papers

NM_002740.6

p.R126S

c.376C>A

1 paper

NM_002740.6

p.R126C

c.376C>T

2 papers

NM_002740.6

p.R127K

c.380G>A

2 papers

NM_002740.6

p.I124V

c.370A>G

5 papers

NM_002740.6

p.R130C

c.388C>T

1 paper

NM_002740.6

p.K122R

c.365A>G

4 papers

NM_002740.6

p.R130H

c.389G>A

1 paper

NM_002740.6

p.W132C

c.396G>C

1 paper

NM_002740.6

p.W132C

c.396G>T

2 papers

NM_002740.6

p.Y136C

c.407A>G

1 paper

NM_002740.6

p.K122Splc

c.365-109T>C

2 papers

NM_002740.6

p.R151H

c.452G>A