Varaico: Literature-Extracted Genetic Variants

PRKCI

174 papers

RefSeq Summary

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involve...

Pfam Domains

PB1aa 25–107UCSCPB1 domain

C1_1aa 141–193UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Pkinaseaa 254–522UCSCProtein kinase domain

Pkinase_Caa 543–584UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase C iota

HGNC Previous Symbol

DXS1179E

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002740.6

p.V186I

c.556G>A

Surrounding Variants

1 paper

NM_002740.6

p.V186F

c.556G>T

1 paper

NM_002740.6

p.T187K

c.560C>A

1 paper

NM_002740.6

p.I188T

c.563T>C

2 papers

NM_002740.6

p.R192W

c.574C>T

1 paper

NM_002740.6

p.R192Q

c.575G>A

1 paper

NM_002740.6

p.H179L

c.536A>T

1 paper

NM_002740.6

p.H193Y

c.577C>T

1 paper

NM_002740.6

p.S194C

c.581C>G

1 paper

NM_002740.6

p.P196S

c.586C>T

1 paper

NM_002740.6

p.P196Q

c.587C>A

2 papers

NM_002740.6

p.P196L

c.587C>T

1 paper

NM_002740.6

p.Q197*

c.589C>T